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Alle Lösungen



Mit unserem Werum PAS-X MES – vor Ort oder in der Cloud installiert – und unseren Softwarelösungen für Datenanalyse, Track & Trace, vernetzte Fabriken und intelligente Verpackungen sind wir der weltweit führende Anbieter und Partner der Pharma- und Biotechindustrie.

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Wir sind Spezialisten für komplette Transportsysteme im Bereich Pharma- und Medizinprodukte. Unsere Lösungen sind maßgebend im Bereich des kontaktlosen und sicheren Transports von z.B. Glasspritzen.

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Als weltweit führender Inspektionsexperte entwicklen wir Lösungen für die Pharma und Biotechindustrie. Unser Angebot reicht von Hochleistungsmaschinen und Halbautomaten über Laboreinheiten bis Inspektionsapplikationen für die Inprozesskontrolle.

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Wir sind führender Anbieter von Verpackungsmaschinen für flüssige und feste pharmazeutische- sowie für medizinische Produkte. Mit unseren Blister-, Sachet- und Stickpackmaschinen bieten wir Lösungen für Primärverpackungen. Unsere Side- und Topload-Kartonierer setzen weltweit Standards für die Sekundärverpackung.

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K.Pak Topload Case Packer

Introducing our latest solution from Körber; the K.Pak Topload Case Packer! Created specifically for the pharmaceutical industry, the K.Pak solution provides operator-friendly machines to complete any production line. Our solution focuses on innovative technology, high-quality design and expert handling and packaging of your product. It’s time to start connecting the dots with Körber!



Als langjährige Spezialisten entwickeln wir Verpackungslösungen für innovative und hochwertige Pharma-Sekundärverpackungen aus Karton. Wir bieten Ihnen Lösungen für Fälschungssicherheit, Standard- Faltschachteln und vieles mehr.

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Unsere Experten beraten Sie nach der Analyse Ihrer Anforderungen, zeigen Ihnen Optimierungspotenziale auf und unterstützen Sie bei der Implementierung von Projekten in allen Bereichen der Pharma-, Biotech- und Medizinproduktindustrie.

Übersicht Beratung

Prof. Dr. Christoph Herwig
Senior Scientific Advisor, Körber-Geschäftsfeld Pharma


Integrated Bioprocess Data Analytics

Bioprocess data creates value for biotech companies. No doubt. Accelerated process development. Investigation & troubleshooting. Operations excellence. Assess optimization potential. Just to name a few use cases. Industry 4.0. Digitalization of the processing environment. New sensor technologies and data integrity requirements disrupt how process data is managed and analyzed. As a result, requirements for data management and bioprocess data analytics change dramatically. Today, data sources are very complex and multidimensional. Spectra from spectroscopic sensors, such as NIR and Raman, images from flow cytometry and in-line microscopes, mass spectrometry chromatograms, time-series sensor data, quality data, software sensors. Upstream. Downstream. Just to name a few. New solutions capable of managing and analyzing all process-relevant data types are necessary.

Process data is now multidimensional and of multiple origins

Industry 4.0 and process digitalization brought birth to new process analytical technologies. Processes are better monitored than ever before. The technological possibilities to mine chemical-, physical- and biological data from manufacturing are cheaper and more accurate than ever before. A great quantity of big process data is collected on a routine basis. But data size is not the issue. Data sources are now multidimensional and need to be aligned holistically, contextualized for doing value-added bioprocess data analytics. This is an issue. For integrated bioprocess data analytics, we need to wrangle all relevant data sources. The images below give a brief overview of data types you encounter in bioprocessing.

The new data sources and novel sensor technologies require new ways to analyze data. So far, nobody can analyze spectral data, sensor data, and quality data simultaneously. Data is in multiple database systems. Data needs to be combined and restructured for the analysis. This is data wrangling.

The most common way to wrangle data today is in spreadsheets. Data is imported from various historians, time-series databases, LIMS, or MES systems. Then an engineer or process data analyst sits for weeks wrangling the data. As a result, he has a nice spreadsheet. A spreadsheet nobody else can reuse. No data integrity is given. No traceability of the process is provided; significant data sets from 2D and 3D data are still left out. Today engineers and process analysts spend most of their time wrangling with spreadsheets. For more complex data sources, it is even impossible to use spreadsheets.

“Era of Industry 4.0. Analytics of process data using spreadsheets is not feasible anymore.”

But how to deal with the new wave of complex data sources? How to wrangle spectral, time-series, picture, and document information? How to mine information and bring this data in a combined form for dashboarding, analytics, and reporting?

Analyze spectral, image, and time-series process data in one step

The solution is integrated bioprocess data analytics. Integrated bioprocess data analytics takes data from time-series databases, spectral databases, MES systems, and LIMS systems. Data is wrangled to be available for bioprocess data analytics. Unique to integrated bioprocess data analytics is the capability to mine features (so-called Process Performance Indicators = PPI) from the data sources. For example, time-series data is condensed to single values of PPIs with high meaning, such as mean, median, average, and standard deviations.

A new way for bioprocess data analytics – integrated data analytics

The same we do for document/ image information. Algorithms mine PPIs from images. We extract features such as roughness, compactness, saturation. The same happens for spectral or chromatography data, in which not only peak heights bus also 1st and 2nd derivatives and tailing features. Algorithms mine PPIs from spectral data. This happens in a feature mining engine dedicated to mining PPIs from complex datasets. As a result, you have process performance indicators from your datasets.

Based on process performance indicators, bioprocess data analytics is easy. You can dashboard your PPIs to perform technology transfers, scale-up, process characterization , and continued process verification. You can provide visual analytics for engineers and scientists or let data scientists access this information to run predictive and machine learning algorithms.

  • Data wrangling
    Complex data is wrangled in a system capable of dealing with time series, image, and spectral data. Data is contextualized and ready for value-added data analytics.
  • Process Performance Indicators (PPIs)
    A feature mining engine mines process performance indicators from sensor data, images, and pictures
  • Data Analytics
    Scientists/ engineers and managers analyze process performance indicators for the entire process chain

PAS-X Savvy software for integrated bioprocess data analytics

PAS-X Savvy software is the first software platform dedicated to integrated process analytics based on holistic PPI analysis. Wrangle and analyze all process-relevant data sources. The unique feature mining engine enables the process of complex data to easily accessible PPIs. Dashboard and multivariate analytics functionality. Analyze all your data. Fast. Intuitive. In Real-time.

Request a personal demo

We’d love the opportunity to demo PAS-X Savvy to your team, answer your questions and explore whether PAS-X Savvy® would be a good fit. Request a demo now, and one of our experts will get in touch with you shortly.

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