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We have a solution for everything – and the corresponding experience. In our current seven areas of expertise, we are at your disposal with our comprehensive know-how.

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24/7 available for you: In our virtual showroom, we present our extensive portfolio and latest innovations. 

Software

Software

With our PAS-X Manufacturing Execution System (MES) and software solutions for Analysis, Track & Trace, Networked Factories, and Intelligent Packaging, we are the world's leading supplier and partner to the pharmaceutical and biotech industries.

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Handling

Handling

We are specialists for complete handling systems for pharmaceutical and medical products. Our solutions are decisive in the field of contactless and safe transport of e.g. glass syringes.

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Inspection

Inspection

As the world's leading inspection expert, we develop solutions for the pharmaceutical and biotech industries. Our range of products extends from high-performance machines and semi-automatic machines to laboratory units and inspection applications for in-process control.

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Packaging materials

Packaging materials

As long-standing specialists, we develop packaging solutions for innovative and high-quality secondary pharmaceutical packaging made of cardboard. We offer you solutions for counterfeit protection, standard folding boxes and much more.

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Services

You need help with a specific product or have questions about one of our areas of expertise? Take advantage of our extensive range of services, we will support you quickly and easily.

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Inspection

Inspection

We offer our customers a wide range of inspection solutions and quality controls at the highest level. Learn more about the right technology for your requirements.

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Packaging machines

Packaging machines

Our packaging machines ensure maximum flexibility and productivity for your packaging processes. Learn more about our modular, customer-specific packaging solutions.

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Packaging materials

Packaging materials

The demands on pharmaceutical packaging are high: it should be forgery-proof and childproof, but also compact and sustainable. Find out here how we make packaging future-proof.

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About us

We at Körber in the Pharmaceuticals business area are the people to contact when it comes to pharmaceutical products. As a leading system provider, we advise our customers from the development and production to the inspection and packaging of their products.

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Media center

In our Mediacenter you will find all content related to our webinars, product and brand information such as downloads, videos and the Virtual Showroom collected in one place.

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References

References

Would you like to know how we have solved different customer requirements sustainably and efficiently? 
What project partners say about us or which industry awards our innovations have received? 

Christoph Herwig
Prof.

Blog

Integrated Bioprocess Data Analytics

Bioprocess data creates value for biotech companies. No doubt. Accelerated process development. Investigation & troubleshooting. Operations excellence. Assess optimization potential. Just to name a few use cases. Industry 4.0. Digitalization of the processing environment. New sensor technologies and data integrity requirements disrupt how process data is managed and analyzed. As a result, requirements for data management and bioprocess data analytics change dramatically. Today, data sources are very complex and multidimensional. Spectra from spectroscopic sensors, such as NIR and Raman, images from flow cytometry and in-line microscopes, mass spectrometry chromatograms, time-series sensor data, quality data, software sensors. Upstream. Downstream. Just to name a few. New solutions capable of managing and analyzing all process-relevant data types are necessary.

Process data is now multidimensional and of multiple origins

Industry 4.0 and process digitalization brought birth to new process analytical technologies. Processes are better monitored than ever before. The technological possibilities to mine chemical-, physical- and biological data from manufacturing are cheaper and more accurate than ever before. A great quantity of big process data is collected on a routine basis. But data size is not the issue. Data sources are now multidimensional and need to be aligned holistically, contextualized for doing value-added bioprocess data analytics. This is an issue. For integrated bioprocess data analytics, we need to wrangle all relevant data sources. The images below give a brief overview of data types you encounter in bioprocessing.

The new data sources and novel sensor technologies require new ways to analyze data. So far, nobody can analyze spectral data, sensor data, and quality data simultaneously. Data is in multiple database systems. Data needs to be combined and restructured for the analysis. This is data wrangling.

The most common way to wrangle data today is in spreadsheets. Data is imported from various historians, time-series databases, LIMS, or MES systems. Then an engineer or process data analyst sits for weeks wrangling the data. As a result, he has a nice spreadsheet. A spreadsheet nobody else can reuse. No data integrity is given. No traceability of the process is provided; significant data sets from 2D and 3D data are still left out. Today engineers and process analysts spend most of their time wrangling with spreadsheets. For more complex data sources, it is even impossible to use spreadsheets.

“Era of Industry 4.0. Analytics of process data using spreadsheets is not feasible anymore.”

But how to deal with the new wave of complex data sources? How to wrangle spectral, time-series, picture, and document information? How to mine information and bring this data in a combined form for dashboarding, analytics, and reporting?

Analyze spectral, image, and time-series process data in one step

The solution is integrated bioprocess data analytics. Integrated bioprocess data analytics takes data from time-series databases, spectral databases, MES systems, and LIMS systems. Data is wrangled to be available for bioprocess data analytics. Unique to integrated bioprocess data analytics is the capability to mine features (so-called Process Performance Indicators = PPI) from the data sources. For example, time-series data is condensed to single values of PPIs with high meaning, such as mean, median, average, and standard deviations.

A new way for bioprocess data analytics – integrated data analytics

The same we do for document/ image information. Algorithms mine PPIs from images. We extract features such as roughness, compactness, saturation. The same happens for spectral or chromatography data, in which not only peak heights bus also 1st and 2nd derivatives and tailing features. Algorithms mine PPIs from spectral data. This happens in a feature mining engine dedicated to mining PPIs from complex datasets. As a result, you have process performance indicators from your datasets.

Based on process performance indicators, bioprocess data analytics is easy. You can dashboard your PPIs to perform technology transfers, scale-up, process characterization , and continued process verification. You can provide visual analytics for engineers and scientists or let data scientists access this information to run predictive and machine learning algorithms.

  • Data wrangling
    Complex data is wrangled in a system capable of dealing with time series, image, and spectral data. Data is contextualized and ready for value-added data analytics.
  • Process Performance Indicators (PPIs)
    A feature mining engine mines process performance indicators from sensor data, images, and pictures
  • Data Analytics
    Scientists/ engineers and managers analyze process performance indicators for the entire process chain

PAS-X Savvy software for integrated bioprocess data analytics

PAS-X Savvy software is the first software platform dedicated to integrated process analytics based on holistic PPI analysis. Wrangle and analyze all process-relevant data sources. The unique feature mining engine enables the process of complex data to easily accessible PPIs. Dashboard and multivariate analytics functionality. Analyze all your data. Fast. Intuitive. In Real-time.

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We’d love the opportunity to demo PAS-X Savvy to your team, answer your questions and explore whether PAS-X Savvy® would be a good fit. Request a demo now, and one of our experts will get in touch with you shortly.

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