Would you like to know in advance how much product yield you can expect from your commercial process chromatography? With Werum PAS-X Chromatography Control you can look into the future and make reliable pooling decisions based on yield and product purity.
The downstream processing of biotechnologically produced pharmaceuticals or active ingredients often counts for the most challenging part of any bioprocess. Chromatography is considered one of the most established separation methods, both for the initial isolation of the product and for the subsequent, often multi-tiered fine purification.
The target product should be present at the end of chromatographic purification in maximum yield and purity as specified. Yield loss constitutes a significant cost factor, especially on a commercial scale. Process- or product-related contaminations are not only a potential hazard for patients, but also result in considerable additional costs for extensive OOX investigations or, in the worst case, the disposal of an entire batch if the defined specification is exceeded.
In order to make the cost- and time-intensive purification process more economical and streamlined, the continuous optimization of individual isolation and purification sequences is a necessary measure. The yield/purity ratio is the key aspect in the field of chromatography and the basis for optimization approaches. Werum PAS-X Chromatography Control is designed to help you get the most out of your industrial process chromatography.
With our combination of proven artificial intelligence, high-performance real-time analysis and smart recommendations for action, you can make yield- and product purity-related pooling decisions – at an early stage, objectively and reproducibly.