Solutions

We have a solution for everything – and the corresponding experience. In our current seven areas of expertise, we are at your disposal with our comprehensive know-how.

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24/7 available for you: In our virtual showroom, we present our extensive portfolio and latest innovations. 

Software solutions

Software solutions

With our Werum PAS-X MES - on premise or cloud-based - and our software solutions for analysis, track & trace, networked factories, and intelligent packaging, we are the world's leading supplier and partner to the pharmaceutical and biotech industries.

Overview Software solutions

Handling systems

Handling systems

We are specialists for complete handling systems for pharmaceutical and medical products. Our solutions are decisive in the field of contactless and safe transport of e.g. glass syringes.

Overview Handling systems

Inspection machines

Inspection

As the world's leading inspection expert, we develop solutions for the pharmaceutical and biotech industries. Our range of products extends from high-performance machines and semi-automatic machines to laboratory units and inspection applications for in-process control.

Overview Inspection

Machine finder

Packaging machines

Packaging machines

We are a leading supplier of packaging machines for liquid and solid pharmaceutical and medical products. With our blister, sachet and stick packaging machines we offer solutions for primary packaging. Our side and topload cartoners set standards worldwide for secondary packaging.

Overview Packaging machines

K.Pak Topload Case Packer

Introducing our latest solution from Körber; the K.Pak Topload Case Packer! Created specifically for the pharmaceutical industry, the K.Pak solution provides operator-friendly machines to complete any production line. Our solution focuses on innovative technology, high-quality design and expert handling and packaging of your product. It’s time to start connecting the dots with Körber!

Packaging solutions

Packaging solutions

As long-standing specialists, we develop packaging solutions for innovative and high-quality secondary pharmaceutical packaging made of cardboard. We offer you solutions for counterfeit protection, standard folding boxes and much more.

Overview Packaging solutions

Consulting

Consulting

Our experts will advise you during the analysis of your requirements, show you optimisation potential and support you during the implementation of projects in all areas of the pharmaceutical, biotech and medical device industry.

Overview Consulting

Software

Werum PAS-X Chromatography Control: improved process performance through AI and predictive analytics

Would you like to know in advance how much product yield you can expect from your commercial process chromatography? With Werum PAS-X Chromatography Control you can look into the future and make reliable pooling decisions based on yield and product purity.

The downstream processing of biotechnologically produced pharmaceuticals or active ingredients often counts for the most challenging part of any bioprocess. Chromatography is considered one of the most established separation methods, both for the initial isolation of the product and for the subsequent, often multi-tiered fine purification.

The target product should be present at the end of chromatographic purification in maximum yield and purity as specified. Yield loss constitutes a significant cost factor, especially on a commercial scale. Process- or product-related contaminations are not only a potential hazard for patients, but also result in considerable additional costs for extensive OOX investigations or, in the worst case, the disposal of an entire batch if the defined specification is exceeded.

In order to make the cost- and time-intensive purification process more economical and streamlined, the continuous optimization of individual isolation and purification sequences is a necessary measure. The yield/purity ratio is the key aspect in the field of chromatography and the basis for optimization approaches. Werum PAS-X Chromatography Control is designed to help you get the most out of your industrial process chromatography.

With our combination of proven artificial intelligence, high-performance real-time analysis and smart recommendations for action, you can make yield- and product purity-related pooling decisions – at an early stage, objectively and reproducibly.

lPAS-X Chromatography Control pairs proven artificial intelligence with high-performance real-time analysis and smart action recommendations to optimize your GMP downstream process with ease and speed.r

Bennett Dams, Associate Product Owner Software, Körber Business Area Pharma

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The artificial intelligence of PAS-X Chromatography Control is based on Deep Learning, a specific form of machine learning with an artificial neural network architecture. 
Our data science and AI experts first train the neural network using historical chromatography data as a reference. The prediction model adapted to the data is then validated, verified for its predictive quality and further quality criteria, and then integrated into the purification process. In combination with a defined set of rules and current chromatography data, PAS-X Chromatography Control can now anticipate the most suitable time for fractionation of your product based on the expected product yield and purity – with a prediction quality of more than 95 percent!

This makes PAS-X Chromatography Control a powerful tool for supervising your chromatographic purification process. You will be able to react to process irregularities at an early stage or even, ultimately, to integrate model-based predictive control into your purification in combination with your process control system. 

lIn addition to chromatographic purification techniques, artificial neural networks offer considerable potential in the development of models for various unit operations in a biotechnological manufacturing process with animal cell cultures or microorganisms. r

Matthias Zahn, Senior Data Scientist Software, Körber Business Area Pharma

Contact us for a first, no-obligation consultation for your production process!

PAS-X Chromatography Control supports professionals in their decisions with smart recommendations for action.

PAS-X Chromatography Control is a field-proven product that is under continuous development with a leading multinational pharmaceutical and life science company based in Germany. The individual isolation and purification steps of the large-scale plant for the biotech production of active ingredients are very complex and require a thorough understanding of all parameters involved. Until now, experienced employees determined the start and end times for chromatographic fractionation and separation of the active ingredient based on IPC data. 

With Werum PAS-X Chromatography Control, the company has found an innovative way to support the professionals involved in their decisions, to eliminate potential sources of variability in this important process phase, and to significantly increase product yields while maintaining purity.

Your benefits

Improved process performance

Make use of our AI with your real-time data to reproducibly achieve the perfect balance of yield and purity.

Sound decisions

Always make the best calls with smart recommended actions from our expert system.  

Preventive process control

Respond early to process irregularities with our high-performance and predictive real-time analysis.

Werum PAS-X Intelligence Suite

Individually configurable – discover more solutions from our Werum PAS-X Intelligence Suite for data analysis, data evaluation and process improvement of your pharmaceutical and biopharmaceutical production.

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Werum PAS-X Quality Reporting

Would you like to compile quality reports more efficiently and eliminate errors at the same time? Werum PAS-X Quality Reporting creates your quality reports automatically – with just one click.

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Werum PAS-X Savvy

Accelerate your product commercialization. With Werum PAS-X Savvy you will manage, visualize and analyze your bioprocess technology data in real time.

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Any questions?

Get in contact with us. We are happy to advise you about our solutions and services.

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